空之客2021-09-07 12:18
AAV的安全性风险简直阴魂不散,去年Nat Bio上AAV8/9的动物试验出现大比例的整合进基因组,如今$拜玛林制药(BMRN)$ 的AAV5又被重锤、临床被叫停,感觉越来越有要坐实的趋势(至少对于现有的野生血清型)。
BMN307是一款以AAV5为载体、针对苯丙氨酸氢化酶基因的基因治疗药物,用于治疗苯丙酮尿症...查看全文
阿饭同学2021-01-28 08:27
这个体现了美国人民的革命精神,总要找个地方发泄下巨大的社会矛盾//@雷动九天:回复@流放疯:他们是一帮赌徒,信奉YOLO主义——You only live once,你只活一次。所以干票大的。
成了,就坐上游艇自此退休,不成,大不了变成穷光蛋。
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You onl...查看全文
韬光养晦慢慢来2021-01-27 23:44
信奉YOLO主义——You only live once,你只活一次。所以干票大的。
成了,就坐上游艇自此退休,不成,大不了变成穷光蛋。
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You only live once,你只活一次。所以干票大的。查看全文
$星火治疗(ONCE)$ SC TO-T - Tender offer statement by Third Party Filed: 2019-03-07 AccNo: 0001193125-19-066373 Size: 972 KB 网页链接
$星火治疗(ONCE)$ SC 14D9 - Solicitation, recommendation statements Filed: 2019-03-07 AccNo: 0001193125-19-066393 Size: 551 KB 网页链接
$星火治疗(ONCE)$ SC 13D/A [Amend] - General statement of acquisition of beneficial ownership Filed: 2019-03-07 AccNo: 0001193125-19-066648 Size: 35 KB 网页链接
$星火治疗(ONCE)$ 10-K - Annual report [Section 13 and 15(d), not S-K Item 405] Filed: 2019-02-28 AccNo: 0001609351-19-000042 Size: 11 MB 网页链接
$星火治疗(ONCE)$ SC TO-C - Written communication relating to an issuer or third party Filed: 2019-02-25 AccNo: 0000950103-19-002292 Size: 124 KB 网页链接
$星火治疗(ONCE)$ SC14D9C - Written communication relating to third party tender offer Filed: 2019-02-25 AccNo: 0001193125-19-050033 Size: 181 KB 网页链接
$星火治疗(ONCE)$ SC14D9C - Written communication relating to third party tender offer Filed: 2019-02-25 AccNo: 0001193125-19-050035 Size: 115 KB 网页链接
$星火治疗(ONCE)$ 8-K - Current report Filed: 2019-02-25 AccNo: 0001193125-19-048943 Size: 543 KBItem 1.01: Entry into a Material Definitive AgreementItem 5.03: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal YearItem 7.01: Regulation FD DisclosureItem 9.01...
$星火治疗(ONCE)$ SC14D9C - Written communication relating to third party tender offer Filed: 2019-02-25 AccNo: 0001193125-19-048948 Size: 8 KB 网页链接
$星火治疗(ONCE)$ SC14D9C - Written communication relating to third party tender offer Filed: 2019-02-25 AccNo: 0001193125-19-048950 Size: 17 KB 网页链接