chuminhua2022-01-11 10:18
1月10日,Allogene Therapeutics 表示, FDA 已经解除了去年其整个现货型细胞治疗管道开发的临床暂停。该公司在 10 月披露,美国监管机构已命令其暂停所有五项 AlloCAR T 临床试验,以调查在早期 ALPHA2 接受 ALLO-501A CAR-T 细胞治疗的患者中检测到的“染色体异常”学习。
该病例涉及一名难...查看全文
JZee2021-10-08 06:10
CAR-T 又粗大事了,$Allogene疗法(ALLO)$ 异体CAR-T治疗NHL整出一例染色体异常,被FDA叫停了。TALEN这个基因编辑按理比crispr脱靶少,这次大概是双链剪开了就没接上... 可能crispr公司也得跟着跌... $金斯瑞生物科技(01548)$ $复星医药(SH600196)$ clls查看全文
金牛在肩2021-10-08 06:02
$Allogene疗法(ALLO)$ 宣布其异体 CAR T 出现了一例“染色体异常”,但还没有公布具体细节。
Following infusion of ALLO-501A, the patient experienced Grade 1 CRS and Grade 2 ICANS, which required a course of high dose steroid therapy. The patient subsequently developed progress...查看全文
Allogene疗法(ALLO)03-17 05:36
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001737287-23-000025 Size: 8 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 04:57
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000492 Size: 5 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 05:12
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001737287-23-000024 Size: 6 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 04:51
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000491 Size: 5 KB 网页链接查看全文
禅禅流水2021-10-08 22:24
$Allogene疗法(ALLO)$ 这会儿跌43%。三年前高瓴的会议上那位华裔CEO,David Chang的演讲还历历在目。//@禅禅流水:回复@金牛在肩:以君子之心,异体通用技术遇险,可能推迟,甚至无法为CAR-T降低成本惠及更多病患。殊为可惜。愿Allogene的David Chang挺住!
以小人之心,异体通用技术出险,利好$...查看全文
Allogene疗法(ALLO)03-11 05:06
$Allogene疗法(ALLO)$ 8-K Current report, item 7.01 Accession Number: 0001737287-23-000023 Act: 34 Size: 165 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 05:36
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001737287-23-000025 Size: 8 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 05:12
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001737287-23-000024 Size: 6 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 04:57
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000492 Size: 5 KB 网页链接查看全文
Allogene疗法(ALLO)03-17 04:51
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000491 Size: 5 KB 网页链接查看全文
Allogene疗法(ALLO)03-11 05:06
$Allogene疗法(ALLO)$ 8-K Current report, item 7.01 Accession Number: 0001737287-23-000023 Act: 34 Size: 165 KB 网页链接查看全文
Allogene疗法(ALLO)03-01 05:36
$Allogene疗法(ALLO)$ S-8 Securities to be offered to employees in employee benefit plans Accession Number: 0001737287-23-000020 Act: 33 Size: 133 KB 网页链接查看全文
Allogene疗法(ALLO)03-01 05:27
$Allogene疗法(ALLO)$ 10-K Annual report [Section 13 and 15(d), not S-K Item 405] Accession Number: 0001737287-23-000018 Act: 34 Size: 12 MB 网页链接查看全文
Allogene疗法(ALLO)03-01 05:12
$Allogene疗法(ALLO)$ 8-K Current report, items 2.02 and 9.01 Accession Number: 0001737287-23-000017 Act: 34 Size: 267 KB 网页链接查看全文
Allogene疗法(ALLO)02-15 06:18
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000317 Size: 4 KB 网页链接查看全文
Allogene疗法(ALLO)02-14 05:36
$Allogene疗法(ALLO)$ SC 13G/A [Amend] Statement of acquisition of beneficial ownership by individuals Accession Number: 0001193125-23-035914 Act: 34 Size: 93 KB 网页链接查看全文
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001737287-23-000025 Size: 8 KB 网页链接
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001737287-23-000024 Size: 6 KB 网页链接
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000492 Size: 5 KB 网页链接
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000491 Size: 5 KB 网页链接
$Allogene疗法(ALLO)$ 8-K Current report, item 7.01 Accession Number: 0001737287-23-000023 Act: 34 Size: 165 KB 网页链接
$Allogene疗法(ALLO)$ S-8 Securities to be offered to employees in employee benefit plans Accession Number: 0001737287-23-000020 Act: 33 Size: 133 KB 网页链接
$Allogene疗法(ALLO)$ 10-K Annual report [Section 13 and 15(d), not S-K Item 405] Accession Number: 0001737287-23-000018 Act: 34 Size: 12 MB 网页链接
$Allogene疗法(ALLO)$ 8-K Current report, items 2.02 and 9.01 Accession Number: 0001737287-23-000017 Act: 34 Size: 267 KB 网页链接
$Allogene疗法(ALLO)$ 4 Statement of changes in beneficial ownership of securities Accession Number: 0001593968-23-000317 Size: 4 KB 网页链接
$Allogene疗法(ALLO)$ SC 13G/A [Amend] Statement of acquisition of beneficial ownership by individuals Accession Number: 0001193125-23-035914 Act: 34 Size: 93 KB 网页链接