$Nabriva Therapeutics plc - Ordinary Shares(NBRV)$ Liver tox. 1 case of >10x ALT as well as AST.Worse liver tox numbers for lefamulin at 5x and 10x, but none met Hy's law. 10X diarrhea and 1 case of cdiff. 股价大跌是因为药物的安全表现有瑕疵。这就是没有公司愿意做抗生素的原因，临床试验花的钱都差不多，过FDA的难度也差不多，最后药还卖不出去。$Paratek Pharmaceuticals, Inc. (PRTK)$ $Tetraphase Pharmaceuticals, Inc. (TTPH)$