Zepzelca (lurbinectedin):
Zepzelca net product sales were $246.8 million in 2021, the first full calendar year on the market following launch in July 2020, and increased 21% to $64.8 million in 4Q21 compared to 4Q20.The Company is pleased to have established Zepzelca as the treatment of choice in the second-line SCLC setting after only eighteen months on the market.Zepzelca development program updates:The Company has initiated the Phase 2 basket trial evaluating Zepzelca as monotherapy in select relapsed/refractory solid tumors.Jazz and collaborator F. Hoffmann-La Roche Ltd (Roche) have initiated a Phase 3 trial to evaluate first-line use of Zepzelca in combination with Tecentriq® (atezolizumab), compared to Tecentriq alone, as maintenance therapy, in patients with extensive-stage SCLC after induction chemotherapy. The first patient was enrolled in November 2021.The Company's partner, PharmaMar, initiated a confirmatory trial, LAGOON, in second-line SCLC in December 2021. If positive, this trial would confirm the benefit of Zepzelca in the treatment of SCLC when patients progress following first-line treatment with a platinum-based regimen. $绿叶制药(02186)$
智通财经APP讯,绿叶制药(02186)公布,集团由Pharma Mar,S.A.(Pharma Mar)许可引进的产品注射用Lurbinectedin(LY01017)已在中国香港地区提交新药上市申请,用于治疗接受铂类药物化疗期间或期后出现疾病进展的复发性小细胞肺癌(SCLC)成人... 网页链接