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$Vir Biotechnology(VIR)$

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姗姗来迟的Vir的新冠抗体终于也成功了![哭泣]

在不住院的病人中使用VIR-7831可降低85%的住院和死亡率。

体外实验也表明,VIR-7831抗体对目前的英国,南非和巴西变异病毒都有效。

VIR-7831不但可以阻止病毒入侵健康的细胞,还可以帮助T细胞清除受感染的细胞。靶向的是病毒高度保守的区域,因此理论上还可以防住其它SARS类病毒,比如原SARS病毒。


The IDMC recommendation was based on an interim analysis of data from 583 patients enrolled in the COMET-ICE trial, which demonstrated an 85% (p=0.002) reduction in hospitalization or death in patients receiving VIR-7831 as monotherapy compared to placebo, the primary endpoint of the trial. VIR-7831 was well tolerated. As the trial remains ongoing and blinded with patients continuing to be followed for 24 weeks, additional results, including epidemiology and virology data, will be forthcoming once the trial is completed.


The dual-action design of VIR-7831 to both block viral entry into healthy cells and clear infected cells, as well as its high barrier to resistance, are key distinguishing characteristics.

全部讨论

2021-03-11 12:13

Vir这个成功的三期是针对还没住院的但是住院风险很高的人群,比如肥胖,糖尿病,年龄大于55岁。几天前失败的是针对已经住院的患者。
前者效果奇好,后者没有统计上的效果,这和之前的两个新冠病毒抗体的信号是一致的。

2021-03-11 19:38

看来跟之前乙肝的抗体一样,对低浓度的病毒效果比较好,对高浓度的效果一般

2021-03-11 11:48

看来真值得上点仓位博一博。

2021-03-11 11:32

$Vir Biotechnology(VIR)$$阿里拉姆制药(ALNY)$ 合作那个RNAi治新冠怎么没声音了?

2021-03-11 10:41

抗病毒真是厉害,如果乙肝成功了,这股真是这领域的王者

2021-03-11 10:37